Neem’s Role in Cancer Treatment

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The global impact of cancer is extraordinary. Worldwide, cases are expected to increase to 21.7 million with 13 million deaths per year in 2030. 

Various compounds found in neem bark, leaves, seeds, and seed oil have been used to combat cancerous cells with no registered side effects. Neem extracts have also been shown to sensitize cancer cells to immunotherapy and radiotherapy and enhance the efficacy of chemotherapeutic agents.

The Department of Biochemistry and Microbiology from Rochester’s Mayo Clinic have been researching neem since 2013 and are currently engaged in preclinical evaluation of neem’s ability to inhibit prostate cancer tumor growth in mice.

Most recent investigations have focused on nimbolide, an active molecule isolated from neem that is being evaluated as a potential treatment for the highly lethal pancreatic cancer.

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